研究顯示，優質睡眠可能在清除大腦有害物質方面扮演關鍵角色，有助降低失智症風險。

The brain has a unique waste disposal system known as the glymphatic system, which is thought to be more active during sleep. This system uses cerebrospinal fluid to wash away toxins like amyloid beta and tau proteins, which are associated with Alzheimer's disease.

 

Studies in mice have shown that during sleep, the glymphatic system becomes more efficient at removing these toxic proteins. However, the exact mechanisms are still being studied, and findings in humans are less conclusive. Some research indicates that sleep deprivation can lead to an increase in amyloid beta levels in the brain, suggesting that adequate sleep may help in reducing these levels.

 

On the other hand, certain studies have found that the glymphatic system might be more active during waking hours, challenging the idea that sleep is the primary time for brain detoxification. These conflicting results highlight the need for further research to fully understand how sleep affects the brain's ability to clear toxins.

 

研究顯示，優質睡眠可能在清除大腦有害物質方面扮演關鍵角色，有助降低失智症風險。

大腦擁有一個獨特的廢物清除系統，稱為「類淋巴系統」，這個系統被認為在睡眠期間會更為活躍。該系統透過腦脊髓液沖洗掉與阿茲海默症相關的毒素，如β澱粉樣蛋白和濤蛋白。

小鼠實驗發現，睡眠期間類淋巴系統清除這些有毒蛋白質的效率會提升。不過確切機制仍有待研究，且人體實驗結果尚未定論。部分研究指出，睡眠不足會導致大腦中β澱粉樣蛋白水平上升，這暗示充足睡眠可能有助降低這些有害物質的累積。

另一方面，某些研究發現類淋巴系統在清醒時可能更活躍，這對「睡眠是大腦主要排毒時間」的傳統觀點提出挑戰。這些相互矛盾的研究結果顯示，我們需要更多研究才能完全理解睡眠如何影響大腦清除毒素的能力。