科學文獻

按摩皮膚可以使大腦的廢物清除系統效率提高一倍

2025-12-14

Scientists have discovered a remarkable way to double the brain’s waste clearance system—not with drugs or surgery, but simply by massaging the skin.

A team from the Institute for Basic Science (IBS) has shown in mice that gently stimulating the lymphatic vessels under the skin of the face and neck can dramatically boost cerebrospinal fluid (CSF) flow. This process helps flush out toxins and waste products from the brain, including harmful proteins linked to Alzheimer’s disease. Using a specially designed mechanical stimulator, researchers restored CSF drainage to youthful levels in aged mice, suggesting a safe, non-invasive strategy to improve brain health. Even more exciting, the study mapped previously unknown drainage routes from the brain to superficial lymph nodes through facial lymphatics—pathways that remain active even in older animals. This discovery completes the anatomical picture of CSF outflow and hints at future wearable or clinical devices designed to enhance brain cleansing.

While more research is needed before human applications, this gentle mechanical approach may open the door to new therapies aimed at preventing or slowing neurodegenerative conditions like Alzheimer’s and Parkinson’s.

📖 Source: Nature, “Increased CSF drainage by non-invasive manipulation of cervical lymphatics” (June 4, 2025).

What are your thoughts on this non-invasive approach? Could you see this becoming a common wellness practice in the future?

Note: The information presented here is for general knowledge and discussion.

科學家發現了一種非凡的方法，可以使大腦的廢物清除系統效率提高一倍——無需藥物或手術，只需按摩皮膚即可。

日本基礎科學研究所 (IBS) 的研究團隊在小鼠身上發現，輕柔刺激臉部和頸部皮膚下的淋巴管可以顯著促進腦脊髓液 (CSF) 的流動。這個過程有助於清除大腦中的毒素和代謝廢物，包括與阿茲海默症相關的有害蛋白質。研究人員使用特殊設計的機械刺激器，使老年小鼠的腦脊髓液引流恢復到年輕時的水平，這表明該方法是一種安全、非侵入性的改善大腦健康策略。

更令人興奮的是，這項研究繪製出了先前未知的腦脊髓液引流路徑，這些路徑透過臉部淋巴管從大腦引流至表淺淋巴結——即使在老年動物體內，這些通路仍然活躍。這項發現完善了腦脊髓液流出的解剖學圖譜，並為未來旨在增強大腦清潔功能的可穿戴或臨床設備提供了線索。

雖然在應用於人體之前還需要進行更多研究，但這種溫和的機械方法可能會為預防或延緩阿茲海默症和帕金森氏症等神經退化性疾病的新療法打開大門。

📖 來源：Nature，「透過非侵入性操作頸部淋巴管增加腦脊髓液引流」（2025 年 6 月 4 日）。

您對這種非侵入性方法有何看法？您認為它未來會成為一種常見的健康養生方式嗎？

註：此處提供的資訊僅供一般了解和討論之用。