Diabetic Foot Ulcers (DFU) are among the most severe complications of diabetes. Approximately 589 million adults worldwide are living with diabetes, and around 15% will develop a foot ulcer during their lifetime, increasing the risks of infection, amputation, and mortality. According to the IWGDF, one diabetes-related amputation occurs every 20 seconds worldwide. The limited effectiveness of current treatments highlights the need for innovative therapies that promote wound healing and reduce the risk of infection and amputation.
1.International Diabetes Federation. (2024). IDF Diabetes Atlas (11th ed.).
2.Armstrong, D. G., Boulton, A. J. M., & Bus, S. A. (2017). Diabetic foot ulcers and their recurrence. New England Journal of Medicine, 376(24), 2367–2375.
3.International Working Group on the Diabetic Foot (IWGDF). (n.d.). IWGDF Guidelines.
Arthritis is one of the most common chronic musculoskeletal diseases worldwide. Approximately 528 million people are living with osteoarthritis (OA), while more than 18 million people are affected by rheumatoid arthritis (RA). As a leading cause of chronic pain and disability, arthritis continues to create a significant healthcare burden. Innovative therapies that address inflammation and support tissue repair remain an important area of medical development.
1.World Health Organization. (2023). Osteoarthritis fact sheet.
2.Safiri, S., Kolahi, A. A., Smith, E., Hill, C., Bettampadi, D., Mansournia, M. A., et al. (2023). Global, regional and national burden of osteoarthritis 1990–2020 and projections to 2050. The Lancet Rheumatology, 5(9), e508–e522.
3.World Health Organization. (2023). Rheumatoid arthritis fact sheet.